Services provided at this site
Our Cambridge, MA, facility is only a 10 minutes walk from Kendall Square
Our Cambridge, MA, facility is only a 10 minutes walk from Kendall Square, and houses multiple modern preclinical research laboratories providing a wide range of early derisking services.
Our Early Development Services team focuses on a full risk assessment platform for in silico and in vitro services for developability, immunogenicity, stability, antibody humanization, protein engineering and provide non-GMP mammalian and microbial expression services.
Our protein experts can help optimize your drug candidate to give you the best chance for clinical success.
Non-GMP protein expression and product characterization
- Mammalian cell culture (CHO cell lines)
- E.coli expression
- Pichia expression
- Expression quantities from mL to 20L/mg-5g
- Affinity and non-affinity chromatography
- Protein characterization
- Binding affinity analysis
In silico assessment and protein engineering
- Computational analysis of protein sequence and structure
- Antibody humanization and deimmunization
- T cell Immunogenicity risk profiling using proprietary Epibase® platform
- Protein engineering to de-risk development and manufacture
- Aggregation prediction using proprietary Sentinel APART® platform
- Manufacturability assessment
Offerings
Technologies available at this site
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